Thermo Fisher Scientific Calcitonin Receptor Polyclonal Antibody
Rabbit polyclonal antibody targeting human Calcitonin Receptor for WB, IHC, and ICC applications. Affinity-purified, unconjugated form with high specificity. Suitable for research use only; predicted cross-reactivity with monkey, horse, and dog.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide corresponding to Human CALCR (aa 479–493) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA, 30% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2633272 |
Product Specific Information
These polyclonal antibodies are of rabbit origin, developed by immunizing animals with specific proteins or peptides. The antibody is purified by affinity chromatography from rabbit sera and tested for functionality in relevant research applications.
This product is intended for Research Use Only and is non-hazardous, non-infectious in nature.
Predicted to react with Monkey, Horse, and Dog.
Target Information
The Calcitonin Receptor inhibits bone resorption and is expressed during development, playing a role in morphogenesis. Three alternatively spliced isoforms have been identified.
In addition to binding calcitonin, this receptor can complex with RAMP3 (receptor activity modifying protein) to bind amylin, which regulates pancreatic islet function and is implicated in Type II diabetes.
Calcitonin Receptor expression has been reported in artery, blood, bone, brain, kidney, lung, placenta, prostate, skeletal muscle, and thyroid. ESTs have been isolated from bone, embryo, kidney, and melanocyte/uterus/fetal heart libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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