Thermo Fisher Scientific KV4.2 (KCND2) Polyclonal Antibody

Applications

Product Specifications

Product Specific Information

Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: add 50 µL of deionized water.

Target Information

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.

Four sequence-related potassium channel genes—shaker, shaw, shab, and shal—have been identified in Drosophila, and each has human homolog(s).
This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential.
This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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