Thermo Fisher Scientific KCNQ1 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: add 50 µL of deionized water.

Target Information

Voltage-gated K⁺ channels in the plasma membrane control repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells.
KCNQ1, together with KCNE1, forms a channel predominantly expressed in the heart and cochlea, regulating the slow depolarization-activated potassium current.
Mutations in KCNQ1 and KCNE1 are associated with cardiac diseases, while KCNQ4 mutations are implicated in deafness.
KCNQ proteins typically contain six transmembrane domains and form tetramers. KCNQ4 can form heteromeric channels with KCNQ3 and is expressed in several tissues, including cochlear outer hair cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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