Thermo Fisher Scientific LPAR4 Polyclonal Antibody
LPAR4 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 다양한 종에 반응하며 IHC 및 Flow Cytometry에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 장기 보관 시 -20°C에서 안정적 유지.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bat, Hamster, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 19 amino acid peptide from N-terminal extracellular domain of human LPAR4 / GPR23 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551263 |
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bat, Hamster (100%).
Target Information
EDG4 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids.
There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis.
They also evoke cellular effector functions dependent on cytoskeletal responses such as contraction, secretion, adhesion, and chemotaxis.
EDG receptors are developmentally regulated and differ in tissue distribution.
They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases.
EDG4 is expressed in testes, ovarian tumor, and leukocyte-containing tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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