Thermo Fisher Scientific LPAR4 Polyclonal Antibody
LPAR4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 다양한 종에서 반응하며, 항원 친화 크로마토그래피로 정제됨. IHC(P)에서 10–20 µg/mL 농도로 사용. 연구용으로만 제공, 진단용 불가.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 10–20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Human, Pig, Rabbit |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from C-Terminus of human LPAR4 / GPR23 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551265 |
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Elephant, Panda, Bovine, Dog, Rabbit, Pig (100%).
Target Information
EDG4 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. There are eight known members of the EDG receptor family, implicated in mediating growth-related effects such as induction of cellular proliferation, differentiation, survival, and suppression of apoptosis. They also evoke cellular effector functions dependent on cytoskeletal responses such as contraction, secretion, adhesion, and chemotaxis.
EDG receptors are developmentally regulated and differ in tissue distribution, coupling to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases.
EDG4 is expressed in testes, ovarian tumor, and leukocyte-containing tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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