Thermo Fisher Scientific LINGO1 Polyclonal Antibody
LINGO1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 검증됨. 인간 및 다양한 종에 반응하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Chicken, Human, Mouse, Non-human primate, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from C-terminus of human LINGO1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551260 |
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Monkey, Marmoset, Mouse, Rat, Elephant, Panda, Bovine, Pig, Opossum, Turkey, Chicken (100%).
Target Information
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) involved in RhoA activation, contributing to inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Acts as a negative regulator of oligodendrocyte differentiation and axonal myelination (PubMed:15895088). Functions with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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