Thermo Fisher Scientific NME1 Recombinant Rabbit Monoclonal Antibody (011)
인간 NME1/NDKA 단백질을 인식하는 재조합 토끼 단클론 항체. Western blot 및 Immunocytochemistry에 적합. 보존제가 없는 액상 형태로 제공되며, 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 011 |
| Immunogen | Recombinant Human NME1/NDKA protein (Ala2–Glu152) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785308 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and expressed in HEK293 cells. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
This antibody has specificity for Human NME1/NDKA.
Target Information
NME1 was identified due to reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of A (encoded by NME1) and B (encoded by NME2) isoforms. Mutations in this gene have been linked to aggressive neuroblastomas. Two transcript variants encoding different isoforms have been identified. Co-transcription with the downstream NME2 gene generates naturally occurring NME1-NME2 fusion transcripts, encoding a fusion protein sharing sequence identity with both gene products.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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