Thermo Fisher Scientific NPC2 Recombinant Rabbit Monoclonal Antibody (012)
Human NPC2 단백질을 인식하는 재조합 토끼 단일클론 항체로, 높은 특이성과 재현성을 제공합니다. Western blot, ELISA, IP 등에 사용 가능하며, 보존제가 포함되지 않아 민감한 실험에 적합합니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:5,000–1:10,000 |
| Immunoprecipitation (IP) | 1–4 µL/mg of lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 012 |
| Immunogen | Recombinant Human NPC2 Protein (Met1–Leu151) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C (avoid freeze/thaw cycles). |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785311 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide (final concentration 0.05%–0.1%) to prevent contamination.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to large rabbit immune repertoire
This antibody specifically recognizes Human NPC2.
Target Information
The NPC2 gene encodes a protein containing a lipid recognition domain that regulates cholesterol transport through the late endosomal/lysosomal system. Mutations in this gene are associated with Niemann-Pick disease type C2 and frontal lobe atrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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