Thermo Fisher Scientific IGHMBP2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.2–1.0 µg/mL

Product Specifications

Product Specific Information

This target displays homology in the following species:
Cow: 100% | Dog: 100% | Guinea Pig: 100% | Human: 100% | Mouse: 100% | Rat: 100%

Target Information

IGHMBP2 is a 5′ to 3′ helicase that unwinds RNA and DNA duplexes in an ATP-dependent reaction. Acts as a transcription regulator and is required for transcriptional activation of the flounder liver-type antifreeze protein gene.
It binds specifically to enhancer element B of the flounder antifreeze protein gene intron and to the insulin II gene RIPE3B enhancer region.
May be involved in translation and binds to 5′-phosphorylated single-stranded guanine-rich sequences related to the immunoglobulin mu chain switch region, preferentially to the 5′-GGGCT-3′ motif.
Interacts with tRNA-Tyr and stimulates transcription of the human neurotropic virus JCV.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 파일명: PA5-68960_IGHMBP2_P40694-1_Rabbit.svg, PA5-68960_IGHMBP2_P40694-1_Rabbit_PDP.jpeg)