Thermo Fisher Scientific BFSP2 Monoclonal Antibody (OTI2B7), TrueMAB
BFSP2 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 최적화되어 있습니다. Human 시료에 반응하며, Lyophilized 형태로 제공됩니다. 고순도 Affinity chromatography 정제 및 PBS buffer(8% trehalose)로 안정화되어 있습니다.
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Applications
- Western Blot (WB): 1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 184–415 of human BFSP2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, an additional desalting step is recommended (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The vertebrate ocular lens is composed mainly of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins—phakinin (the product of the BFSP2 gene) and filensin—are expressed after fiber cell differentiation begins. These proteins form a unique cytoskeletal structure called the beaded filament (BF).
Mutations in the BFSP2 gene have been linked to juvenile-onset progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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