Thermo Fisher Scientific BFSP2 Monoclonal Antibody (OTI4D3), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The vertebrate ocular lens is composed mainly of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins—phakinin (the BFSP2 gene product) and filensin—are expressed after fiber cell differentiation begins. These proteins form a unique cytoskeletal structure known as the beaded filament (BF).
Mutations in the BFSP2 gene are associated with juvenile-onset progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.

For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.