Thermo Fisher Scientific TRIP13 Polyclonal Antibody
인간 TRIP13 단백질에 특이적인 Rabbit Polyclonal 항체로, IHC(P)에서 1:50–1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol, 0.02% sodium azide)에 보관. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TRIP13. Recombinant protein control fragment (Product # RP-103146) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2648957 |
Product Specific Information
Immunogen sequence:
SKWFSESGKL VTKMFQKIQD LIDDKDALVF VLIDEVESLT AARNACRAGT EPSDAIRVVN AVLTQIDQIK RHSNVVILTT SNITEKIDVA FVDRADIKQY IGPPSA
Highest antigen sequence identity:
- Mouse: 98%
- Rat: 98%
Target Information
Thyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner.
TRIP13 (thyroid hormone receptor interactor 13), also known as 16E1BP, is a transcription factor that interacts with the ligand binding domain of the thyroid receptor (TR) as well as a variety of target genes including human papilloma virus type 16 (HPV16) E1.
Unlike most TRIP proteins that function only in the presence of hormones, TRIP13 does not require thyroid hormone to interact with TR. The association of TRIP13 with HPV16 E1 suggests that TRIP13 may have tumor suppressor gene function.
TRIP13 is a 432 amino acid protein with two isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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