Thermo Fisher Scientific NME1 Monoclonal Antibody (01)

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:20–1:100

Flow Cytometry (Flow)

• Tested Dilution: 1:25–1:100

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human NME1/NDKA.

Target Information

NME1 was identified because of its reduced mRNA transcript levels in highly metastatic cells.
Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of A (encoded by this gene) and B (encoded by NME2) isoforms.
Mutations in the gene have been identified in aggressive neuroblastomas.
Two transcript variants encoding different isoforms have been found for this gene.
Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encode a fusion protein comprised of sequence sharing identity with each individual gene product.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.