Thermo Fisher Scientific DYNLRB1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-63 of human DYNLRB1 (NP_0012686561) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DYNLRB1,uniProtId:Q9NP97-1,ncbiNodeId:9606,antigenRange:34-96,antigenLength:96,antigenImageFileName:PA5-90288_DYNLRB1_Q9NP97-1_Rabbit.svg,antigenImageFileNamePDP:PA5-90288_DYNLRB1_Q9NP97-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.77 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806001

Product Specific Information

Immunogen sequence: MDNPTTTQYA SLMHSFILKA RSTVRDIDPQ NDLTFLRIRS KKNEIMVAPD KDYFLIVIQN PTE; Positive Samples: 293T, Mouse brain; Cellular Location: Cytoplasm, cytoskeleton

Target Information

The DYNLRB1 gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.