Thermo Fisher Scientific MEGF10 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 26-160 of human MEGF10 (NP_1158221) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MEGF10,uniProtId:Q96KG7-1,ncbiNodeId:9606,antigenRange:904-1038,antigenLength:1140,antigenImageFileName:PA5-87956_MEGF10_Q96KG7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-87956_MEGF10_Q96KG7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804538

Product Specific Information

Positive Samples: U-251MG, HT-29, MCF7, Mouse brain, Mouse liver, Rat brain; Cellular Location: Basolateral cell membrane, Cell membrane, Cell projection, Single-pass type I membrane protein, phagocytic cup

Immunogen sequence: ADYTISGTLP HSNGGNANSH YFTNPSYHTL TQCATSPHVN NRDRMTVTKS KNNQLFVNLK NVNPGKRGPV GDCTGTLPAD WKHGGYLNEL GAFGLDRSYM GKSLKDLGKN SEYNSSNCSL SSSENPYATI KDPPV

Target Information

This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.