Thermo Fisher Scientific MEGF10 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

ELISA

• Tested Dilution: 1 µg/mL

Product Specifications

Product Specific Information

• Positive Samples: U-251MG, HT-29, MCF7, Mouse brain, Mouse liver, Rat brain
• Cellular Location: Basolateral cell membrane, Cell membrane, Cell projection, Single-pass type I membrane protein, phagocytic cup
• Immunogen Sequence:
  ADYTISGTLP HSNGGNANSH YFTNPSYHTL TQCATSPHVN NRDRMTVTKS KNNQLFVNLK NVNPGKRGPV GDCTGTLPAD WKHGGYLNEL GAFGLDRSYM GKSLKDLGKN SEYNSSNCSL SSSENPYATI KDPPV

Target Information

This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility, and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD), as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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