Thermo Fisher Scientific Biglycan Polyclonal Antibody
Rabbit polyclonal antibody targeting human Biglycan protein. Validated for WB, IHC(P), and Flow Cytometry. Predicted cross-reactivity with mouse, rat, and bovine. Supplied as liquid, 2 mg/mL, unconjugated, stored at 4°C or -20°C. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 148–176 of human Biglycan (BGN) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Ammonium sulfate precipitation, Size-exclusion chromatography, Dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2065197 |
Product Specific Information
This antibody is predicted to react with bovine, mouse, and rat based on sequence homology.
Target Information
Biglycan (BGN) is a small cellular or pericellular matrix proteoglycan structurally related to decorin and fibromodulin. It is believed to arise from a gene duplication event with decorin. While decorin contains one glycosaminoglycan chain, biglycan likely contains two, hence its name. Biglycan functions in connective tissue metabolism by binding to collagen fibrils and modulating growth factor-beta activity. It may also promote neuronal survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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