Thermo Fisher Scientific TRPC5 Monoclonal Antibody (N67/15), PE
TRPC5 단백질을 인식하는 Mouse IgG2b 형 단일클론 항체로, PE 형광 표지되어 있습니다. Western blot, IHC, ICC/IF, IP 등 다양한 분석에 사용 가능하며 인간, 마우스, 랫트에서 반응합니다. 4°C 보관, 단백질 G 정제, 무보존제 포뮬레이션입니다.
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Thermo Fisher Scientific TRPC5 Monoclonal Antibody (N67/15), PE
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | Assay-dependent |
| Antibody Microarray (AM) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N67/15 |
| Immunogen | Synthetic peptide corresponding to amino acids 827–845 of human TrpC5 (short transient receptor potential channel 5, Htrp5) |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931934 |
Available Formats
- Unconjugated (MA5-27657)
- APC (MA5-45477)
- FITC (MA5-45478)
- PerCP (MA5-45479)
- Custom conjugation available upon request
Product Specific Information
1 µg/mL of MA5-45480 was sufficient for detection of TrpC5 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Detects approximately 110 kDa.
Target Information
TRPC5 belongs to the transient receptor potential (TRP) channel family and is one of seven mammalian TRPC proteins. It forms a receptor-activated, non-selective calcium-permeant cation channel and can function alone or as a heteromultimer with TRPC1, TRPC3, and TRPC4.
TRPC5 interacts with proteins such as calmodulin, CABP1, enkurin, NHERF, MX1, RNF24, and SESTD1. It is regulated by phosphatidylinositol second messenger systems activated by receptor tyrosine kinases or G-protein coupled receptors.
Associated diseases include Hypertrophic Pyloric Stenosis and Pyloric Stenosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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