Thermo Fisher Scientific CYP7B1 Monoclonal Antibody (OTI7H10)
Human CYP7B1 단백질을 인식하는 Mouse 모노클로날 항체로, Western blot에 적합. E.coli에서 발현된 재조합 단백질(aa 350-506)을 면역원으로 사용. 액상 형태, 0.63 mg/mL 농도, -20°C 보관. 약물 대사 및 콜레스테롤 경로 연구용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7H10 |
| Immunogen | Recombinant protein expressed in E. coli corresponding to amino acids 350–506 of Cyp7b1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.63 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724185 |
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids.
This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, converting cholesterol to bile acids.
This enzyme likely plays a minor role in total bile acid synthesis but may also be involved in the development of atherosclerosis, neurosteroid metabolism, and sex hormone synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 항체 관련 항원 이미지: MA5-24898_CYP7B1_O75881-1_House_mouse.svg, MA5-24898_CYP7B1_O75881-1_House_mouse_PDP.jpeg)
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