Thermo Fisher Scientific Neurogenin 1 Monoclonal Antibody (OTI15A7)
Neurogenin 1 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC, IP 등 다양한 응용에 사용 가능. 인간 시료에 반응하며, 액상 형태로 제공. 고순도 친화 크로마토그래피 정제 및 안정적인 PBS 버퍼에 보존.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | 2–4 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI15A7 |
| Immunogen | Full-length protein expressed in 293T cells transfected with human NEUROG1 expression vector |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724827 |
Target Information
Neurogenin 1 (NeuroG1) is a basic helix-loop-helix (bHLH) transcription factor involved in cell fate determination during development. It plays dual roles in cell-fate specification—promoting neurogenesis while inhibiting astrocyte differentiation. NeuroG1 functions as a transcriptional activator and regulates the CREB-binding protein transcription complex, thereby influencing neurogenesis and gliogenesis processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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