Thermo Fisher Scientific PROZ Monoclonal Antibody (OTI4F1), TrueMAB
Human PROZ 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI4F1). Western blot과 IHC(P)에서 검증됨. Affinity chromatography로 정제된 1 mg/mL 액상 항체로, PBS/1% BSA/50% glycerol buffer에 보관. 연구용으로 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4F1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 115–400 of human PROZ produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
PROZ (Protein Z) is a vitamin K-dependent plasma glycoprotein of approximately 62 kDa and 396 amino acids. It contains four domains: a Gla-rich region, two EGF-like domains, and a trypsin-like domain lacking the catalytic serine residue.
Although not enzymatically active, it is structurally related to serine proteases in the coagulation cascade (factors VII, IX, X, and protein C).
Protein Z binds phospholipid surfaces through carboxyglutamate residues and plays a role in accelerating the degradation of factor Xa via protein Z-related protease inhibitor (ZPI).
Deficiency of PROZ has been variably associated with both thrombosis and bleeding tendencies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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