Thermo Fisher Scientific TNFSF4 Monoclonal Antibody (OTI5D8), TrueMAB
TNFSF4(OX40L) 단백질을 인식하는 마우스 모노클로날 항체로, Western blot에 적합합니다. 인간 시료에 반응하며, 액상 형태로 공급됩니다. 1 mg/mL 농도로 PBS, BSA, 글리세롤 완충액에 보관되며, -20°C에서 보존합니다.
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Applications
- Western Blot (WB): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5D8 |
| Immunogen | Full length human recombinant protein of human TNFSF4 produced in HEK293T cell. Target family: OX40L (CD252), UniProt ID: P23510-1, Antigen range: 1–183 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The tumor necrosis factor superfamily member TNFSF4 is a type II membrane-bound, non-covalently linked homotrimeric protein. It is expressed on antigen-presenting cells such as dendritic cells and activated B-cells, as well as on vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals through the TNFRSF4 receptor, expressed predominantly on CD4+ T cells and certain activated CD8+ T cells. The TNFRSF4/TNFSF4 interaction provides a costimulatory signal required for effective communication between antigen-presenting cells and T cells, enhancing proliferation, survival, and cytokine expression (RANTES, IL-2, IL-3, IFN-γ). This pathway plays a critical role in immunotolerance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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