Thermo Fisher Scientific WT1 Polyclonal Antibody
Human, Mouse, Rat 등 다양한 종에 반응하는 WT1 폴리클로날 항체입니다. 파라핀 조직의 면역조직화학(IHC) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 농축된 액상 형태로 제공되며 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Thermo Fisher Scientific WT1 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:100–1:1,000
Publications: - [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Wilms Tumor 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.09 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792244 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (97%), Rat (97%), Japanese Medaka (83%), Xenopus laevis (87%), Pig (97%), Chicken (94%).
- Positive Control: Mouse testis, Rat testis.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The Wilms Tumor 1 (WT1) gene encodes one of the WPP domain-interacting proteins required for RanGAP nuclear envelope association in root tip cells.
Ran GTPase plays essential roles in nucleocytoplasmic transport, spindle formation, and postmitotic nuclear envelope reassembly.
The cytoplasmic Ran GTPase activating protein RanGAP is critical for establishing a functional RanGTP/RanGDP gradient across the nuclear envelope.
In Arabidopsis thaliana, RanGAP association with the nuclear envelope requires WPP domain-interacting proteins (WIPs). WT1 and WIT2 have been identified as a second family of CC-TMD proteins necessary for RanGAP nuclear envelope association in root tip cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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