Thermo Fisher Scientific Perilipin 1 Monoclonal Antibody (PERI 112.17)
Perilipin 1 단백질을 인식하는 Mouse monoclonal antibody (Clone PERI 112.17). 인간 및 마우스 시료에 반응하며, IHC(P)와 ICC/IF에 사용 가능. 합성 펩타이드 면역원으로 제작, Affinity chromatography로 정제. PBS/BSA buffer에 보관.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PERI 112.17 |
| Immunogen | Synthetic peptide of perilipin/PLIN1 (duplicated N-terminus of perilipin; aa 1–20) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.5% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Target Information
Adipose tissue functions as an energy reserve and is tightly regulated. Adipocytes produce physiologically important proteins such as lipoprotein lipase (LPL), leptin, Acrp30, resistin, and perilipin.
Perilipin is an intracellular neutral lipid droplet protein localized on the surface of lipid droplets and regulated hormonally. Upon lipolytic stimulation, perilipin is phosphorylated by protein kinase A and modulates hormone-sensitive lipase (HSL), which hydrolyzes triacylglycerol.
Perilipin expression is restricted to adipocytes and steroidogenic cells, with two known isoforms (Perilipin A and B) produced by alternative splicing of a single-copy gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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