Thermo Fisher Scientific Desmocollin 3 Monoclonal Antibody (Dsc3-U114)
Desmocollin 3 단백질을 인식하는 mouse IgG1 단클론 항체로, Western blot, IHC, ICC 등 다양한 응용에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Dilution: Assay-dependent
Immunohistochemistry (IHC)
- Dilution: 1:10–1:100
Immunohistochemistry (Paraffin) (IHC (P))
- Dilution: 1:10–1:100
Immunocytochemistry (ICC/IF)
- Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | Dsc3-U114 |
| Immunogen | Synthetic peptide corresponding to a sequence present on the extracellular anchor domain of human desmocollin 3 (VHGAPFYFSLPNTSPEISRLWSLTKVC) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 0.5% BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
Target Information
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Three desmoglein subfamily members have been identified, all belonging to the cadherin cell adhesion molecule superfamily. These desmoglein genes are clustered on chromosome 18. Desmocollin 3 has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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