Thermo Fisher Scientific VE-cadherin Monoclonal Antibody (BV9)
인간 VE-cadherin을 검출하는 Mouse IgG2a 단클론 항체로, Western blot, ICC/IF, Flow cytometry에 적합합니다. 혈관내피세포 연결 부위 단백질 인식에 특화되어 있으며, 고순도 Protein G 정제 및 안정적 액상 형태로 제공됩니다.
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Thermo Fisher Scientific VE-cadherin Monoclonal Antibody (BV9)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 4 publications |
| Immunocytochemistry (ICC/IF) | 1–5 µg/mL | - |
| Flow Cytometry (Flow) | 0.5–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BV9 |
| Immunogen | Recombinant protein corresponding to the extracellular domain of human VE-Cadherin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2633308 |
Product Specific Information
MA1-198 VE-Cadherin antibody detects human VE-cadherin by western blot, immunofluorescence, and flow cytometry.
This monoclonal antibody recognizes the extracellular domain of the VE-cadherin protein, which is highly expressed at intercellular junctions of vascular endothelial cells such as Huvec.
Target Information
VE-cadherin is a member of the cadherin superfamily located in a six-cadherin cluster on chromosome 16.
It plays a role in loss of heterozygosity events in breast and prostate cancer.
VE-cadherin protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region, and a conserved cytoplasmic tail.
Functioning as a classic cadherin, it mediates homophilic adhesion and contributes to endothelial cell cohesion and intercellular junction organization.
An alternative splice variant has been described, though the full-length sequence has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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