Thermo Fisher Scientific MMP17 Polyclonal Antibody
Human MMP17 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot, IHC, ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되었으며 PBS 기반 버퍼에 보존. HeLa 세포에서 양성 대조로 사용 가능하며 MMP-2 활성화 연구에 유용.
- 카탈로그번호
- PA528219
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 109–438 of Human MMP17 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.74 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545695 |
Product Specific Information
- Recommended positive controls: HeLa
- Predicted reactivity: Mouse (91%), Rat (91%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes including arthritis and metastasis.
Most MMPs are secreted as inactive proproteins that are activated when cleaved by extracellular proteinases.
The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily, but is unique among MT-MMPs as it is GPI-anchored rather than transmembrane.
This protein activates MMP-2 by cleavage.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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