Thermo Fisher Scientific CDC23/APC8 Polyclonal Antibody
CDC23/APC8 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체입니다. Western blot 및 면역침전(IP) 실험에 적합하며, Human에 반응합니다. 항원 친화 크로마토그래피로 정제되었고, 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 275 and 325 of human cell division cycle 23 (anaphase-promoting complex subunit 8) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Bovine
Target Information
Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s), and the ubiquitin-protein ligases (E3s).
Ubr2 (Ubiquitin-protein ligase E3-alpha-2), also known as N-recognin-2, is a 1755 amino acid protein that contains one UBR-type zinc finger and one RING-type zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr2 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins containing destabilizing N-terminal residues, leading to their ubiquitination and subsequent degradation.
Mice lacking Ubr2 are infertile due to defects in male meiosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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