Thermo Fisher Scientific Pembrolizumab Monoclonal Antibody (90G12), MonoRab

Applications

Tested Dilution

Publications

ELISA (ELISA)

0.01-0.1 µg/mL

-

Blocking Assay (BLOCK)

10-50 µg/mL

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Monoclonal

Type

Antibody

Clone

90G12

Immunogen

Pembrolizumab

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/ml.

Pembrolizumab (Keytruda) is a humanized monoclonal antibody that isapproved by the U.S. Food and Drug Administration for the treatment of patientswith unresectable or metastatic melanoma. Pembrolizumab binds to the human cellsurface receptor PD-1 (Programmed Cell Death Protein 1) and blocks itsinteraction with PD-L1, resulting in the activation of T-cell-mediated immuneresponses against tumor cells. GenScriptMonoRab™ Anti-Pembrolizumab Antibody (90G12), mAb,Rabbit isproduced from a hybridoma resulting from the fusion of partner andB-lymphocytes obtained from a rabbit immunized with Pembrolizumab.

Target Information

Pembrolizumab (Keytruda) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Pembrolizumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.