Thermo Fisher Scientific Pembrolizumab Monoclonal Antibody (90G12), MonoRab
Pembrolizumab(키트루다)을 인식하는 토끼 단클론 항체로, PD-1과 PD-L1 상호작용 차단 연구에 활용 가능. ELISA 및 차단 분석에 적합하며, 동결건조 형태로 제공. 재구성 후 0.5 mg/mL 농도로 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| ELISA (ELISA) | 0.01–0.1 µg/mL |
| Blocking Assay (BLOCK) | 10–50 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 90G12 |
| Immunogen | Pembrolizumab |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Lyophilized antibody should be reconstituted with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
Pembrolizumab (Keytruda) is a humanized monoclonal antibody approved by the U.S. FDA for the treatment of patients with unresectable or metastatic melanoma. Pembrolizumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, leading to activation of T-cell-mediated immune responses against tumor cells.
GenScript MonoRab™ Anti-Pembrolizumab Antibody (90G12), mAb, Rabbit is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a rabbit immunized with Pembrolizumab.
Target Information
Pembrolizumab (Keytruda) is a humanized monoclonal antibody that binds PD-1, blocking PD-L1 interaction and restoring T-cell activity against tumor cells. It is FDA-approved for use in patients with unresectable or metastatic melanoma.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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