Thermo Fisher Scientific AS160 Polyclonal Antibody
AS160(TBC1D4) 단백질을 인식하는 Goat Polyclonal 항체로, Western blot 및 IHC(Paraffin)에 적합. Human에 반응하며, Peptide ELISA로 검증됨. 액상 형태로 0.5 mg/mL 농도, -20°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (DDPEKIEERKKSK) corresponding to the internal amino acids of TBC1D4 (aa 825–838) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10984922 |
Product Specific Information
- Predicted to react with canine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
AS160 (TBC1D4) is a GTPase-activating protein for RAB2A, RAB8A, RAB10, and RAB14.
Isoform 2 promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation to the plasma membrane, enhancing glucose uptake.
Mutations in this gene are associated with non-insulin-dependent diabetes mellitus 5 (NIDDM5).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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