Thermo Fisher Scientific MUC5B Polyclonal Antibody
인체 MUC5B 단백질을 검출하는 Rabbit Polyclonal Antibody로, WB·IHC·ICC/IF에 적합. 합성 펩타이드 유래 항원 사용, 고순도 친화 크로마토그래피 정제. 액상 형태, -20°C 보관, 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MUC5B (Accession Q9HC84), corresponding to amino acid residues A2102–T2152 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853262 |
Product Specific Information
Antibody detects endogenous levels of total MUC5B.
Target Information
Mucins (MUCs) are heavily glycosylated glycoproteins synthesized as membrane-bound or secreted proteins. They exhibit aberrant expression in various malignancies and normally play a protective role for epithelial tissues in the gastrointestinal, respiratory, and genito-urinary tracts.
Mucins are involved in epithelial renewal, differentiation, cell adhesion, and signaling modulation.
MUC5B is vital for maintaining oral health and may be implicated in respiratory and oral diseases. Its expression has been studied in gastric carcinoma and chronic obstructive pulmonary disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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