Thermo Fisher Scientific LYVE1 Polyclonal Antibody
LYVE1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat에 반응합니다. Western blot, IHC, Flow cytometry 등 다양한 응용에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific LYVE1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | View 4 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:200 | - |
| Flow Cytometry (Flow) | 1:50–1:500 | - |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Dog, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to C-terminal portion of murine LYVE-1 (residues 250–318) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% Sodium Azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2138643 |
Product Specific Information
- Antigen retrieval with sodium citrate buffer (pH 6.0) is recommended for paraffin tissues.
- Suggested positive control: Mouse spleen lysate or protein.
Target Information
LYVE1 is a major receptor for hyaluronan (HA) on lymph vessel walls.
It encodes a 322-residue type I integral membrane glycoprotein with a single Link module, similar to CD44 but specifically localized to lymphatic vessels.
LYVE1 serves as a lymph-specific HA receptor and is a marker for lymphatic endothelium.
It is involved in leukocyte and tumor cell trafficking to lymph nodes.
Associated molecules include LYVE1, PALE, VEGFR3, and podoplanin.
Diseases linked to LYVE1 dysfunction include Complete Androgen Insensitivity Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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