Thermo Fisher Scientific AGR2 Monoclonal Antibody (OTI3F2), TrueMAB
AGR2 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western Blot 및 IHC(Paraffin) 실험에 적합합니다. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도, PBS/BSA/glycerol buffer에 보관되며 인간 시료에 반응합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 21–175 of human AGR2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins involved in metastasis induction and p53 tumor suppressor inhibition. AGR2 may serve as a molecular marker and potential therapeutic target for hormone-responsive breast tumors. It is ubiquitously expressed and upregulated in prostate, breast, lung, renal, and endometrial carcinomas. AGR2 expression is positively correlated with estrogen receptor (ER) and negatively correlated with epidermal growth factor receptor (EGFR).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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