Thermo Fisher Scientific NGB Polyclonal Antibody
인간 및 생쥐 시료에 반응하는 NGB 폴리클로날 항체로, Western blot과 ELISA에 적합합니다. 합성 펩타이드(aa 1-151)를 면역원으로 제작되었으며, 고순도 Affinity Chromatography 정제 제품입니다. 액상 형태로 −20°C 보관하며 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: View 1 publication
ELISA
- Tested Dilution: 1 µg/mL
- Publications: None listed
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to amino acids 1–151 of human NGB (NP_0670801) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.29 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855438 |
Product Specific Information
Immunogen sequence:
MERPEPELIR QSWRAVSRSP LEHGTVLFAR LFALEPDLLP LFQYNCRQFS SPEDCLSSPE FLDHIRKVML VIDAAVTNVE DLSSLEEYLA SLGRKHRAVG VKLSSFSTVG ESLLYMLEKC LGPAFTPATR AAWSQLYGAV VQAMSRGWDG E
Target Information
Globins are a superfamily of gas-binding heme proteins found in bacteria, protists, fungi, plants, and animals. They play diverse roles such as binding, transport, scavenging, detoxification, and sensing of oxygen, nitric oxide, and carbon monoxide.
Neuroglobin (Ngb) is a hexacoordinate hemoglobin predominantly expressed in the vertebrate brain, enhancing oxygen supply to neural components. Its high oxygen affinity suggests a role in neuronal responses to hypoxia or ischemia. In vitro neuronal hypoxia elevates neuroglobin levels, improving neuronal cell survival. The human neuroglobin gene maps to chromosome 14q24 and encodes a 151 amino acid protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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