Thermo Fisher Scientific NLGN4X Polyclonal Antibody
Rabbit polyclonal antibody targeting human NLGN4X (Neuroligin-4, X-linked). Validated for WB and ELISA. High purity via affinity chromatography. Supplied in PBS with 50% glycerol. For research use only.
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- PA5110032
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 697–816 of human NLGN4X (NP_065793.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.58 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855443 |
Product Specific Information
Immunogen sequence:
YYKKDKRRHE THRRPSPQRN TTNDIAHIQN EEIMSLQMKQ LEHDHECESL QAHDTLRLTC PPDYTLTLRR SPDDIPLMTP NTITMIPNTL TGMQPLHTFN TFSGGQNSTN LPHGHSTTRV
Target Information
Neuroligin-4, X-linked (also known as NLGN4X, NLGN4, Neuroligin-4, and Neuroligin 4X) is a postsynaptic cell-adhesion molecule that interacts with presynaptic cell-surface neurexins. These interactions bridge the synaptic cleft and play an essential role in synaptic transmission between neurons.
There are five neuroligin genes in humans: NLGN1, NLGN2, NLGN3, NLGN4X, and NLGN4Y.
Mutations in NLGN3 and NLGN4X are linked to Autism Spectrum Disorders (ASD). Expression of neuroligin-4, X-linked has been reported in human pluripotent stem cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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