Thermo Fisher Scientific Human Artemin, Animal-Free Recombinant Protein, PeproTech
인간 유래 Artemin 재조합 단백질로, E. coli 발현 시스템에서 생산된 동물성 성분 무첨가 제품입니다. 신경세포 생존 연구에 활용되며, ≥98% 고순도와 낮은 엔도톡신 수준을 제공합니다. 기능 분석 및 신경생물학 연구용으로 적합합니다.
- 카탈로그번호
- AF-450-17-xxxxx (3개 옵션)
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human Artemin, Animal-Free Recombinant Protein, PeproTech
Applications
- Functional Assay (Functional)
Tested Dilution: Assay-dependent
Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | E. coli |
| Amino Acid Sequence | AGGPGSRARA AGARGCRLRS QLVPVRALGL GHRSDELVRF RFCSGSCRRA RSPHDLSLAS LLGAGALRPP PGSRPVSQPC CRPTRYEAVS FMDVNSTWRT VDRLSATACG CLG |
| Molecular Weight | 24.2 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 98% (SDS-PAGE gel 및 HPLC 분석 기준) |
| Endotoxin Concentration | < 0.1 EU/µg |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
The functional human Artemin ligand is a disulfide-linked homodimer of two 12.0 kDa polypeptide monomers. Each monomer contains seven conserved cysteine residues, one of which is used for interchain disulfide bridging and the others are involved in intramolecular ring formation known as the cysteine-knot configuration.
Recombinant Human Artemin is a 24.2 kDa, disulfide-linked homodimer formed by two identical 113 amino acid subunits.
This product is shipped at ambient temperature. For storage, handling, and reconstitution information, please see the lot-specific Certificate of Analysis.
Target Information
The protein encoded by this gene is a member of the glial cell line-derived neurotrophic factor (GDNF) family of ligands, which belong to the TGF-beta superfamily of signaling molecules. GDNFs have unique neurotrophic properties and potential use in gene therapy for neurodegenerative diseases.
Artemin supports the survival of various peripheral neuron populations and dopaminergic CNS neurons. Its role in the PNS and CNS is substantiated by its expression near these neurons. This protein acts as a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.