Thermo Fisher Scientific Human CNTF, Animal-Free Recombinant Protein, PeproTech
인체 유래 CNTF 재조합 단백질로, 동물 유래 성분이 없는 고순도 제품입니다. 인간 TF-1 세포 증식을 유도하는 생물학적 활성을 보유하며, 신경세포 생존 및 분화 연구에 적합합니다. E. coli 발현, 98% 이상 순도, 실온 배송 및 -20°C 보관.
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Applications
Functional Assay (Functional)
- Assay-dependent
In vitro Assay (IV)
- Refer to publications (4 available)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Published Species | Human, Mouse, Non-human primate |
| Expression System | E. coli |
| Amino Acid Sequence | AFTEHSPLTP HRRDLCSRSI WLARKIRSDL TALTQSYVKH QGLNKNINLD SADGMPVAST DQWSQLTQAQ RLQQNLQAYR TFHVLLARLL QDQQVHFTPT QGDFHQAIHT LLLQVAAFAY QIQQLMILLQ YKIPRNQADG MPINVGDGGL FQKKLWGLKV LQQLSQWTVR SIHDLRFISS HQTGIPARGS HYIANNKKM |
| Molecular Weight | 22.8 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 98% by SDS-PAGE gel and HPLC analyses |
| Endotoxin Concentration | <0.1 EU/µg |
| Activity | Stimulates proliferation of human TF-1 cells (ED50: 50–150 ng/ml) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
Recombinant Human CNTF is synthesized as a 199 amino acid polypeptide (22.8 kDa) lacking a hydrophobic N-terminal signal for secretion.
This product is shipped at ambient temperature. For storage, handling, and reconstitution information, please refer to the lot-specific Certificate of Analysis.
Target Information
The protein encoded by this gene is a polypeptide hormone primarily active in the nervous system, promoting neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. It functions as a potent survival factor for neurons and oligodendrocytes and may help reduce tissue destruction during inflammatory attacks.
A mutation in this gene causing aberrant splicing leads to ciliary neurotrophic factor deficiency, though not directly linked to neurologic disease.
A read-through transcript variant composed of ZFP91 and CNTF sequences has been identified and is considered non-coding. Similar read-through transcription has been observed in mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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