Thermo Fisher Scientific MUC2 Recombinant Rabbit Monoclonal Antibody (JA10-92)
Recombinant rabbit monoclonal antibody targeting human MUC2. Validated for WB, IHC, ICC/IF, and Flow Cytometry. Offers high specificity, sensitivity, and lot-to-lot consistency. Suitable for research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JA10-92 |
| Immunogen | Synthetic peptide within Human MUC2 aa 5100–5149 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809931 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the larger rabbit immune repertoire
Target Information
Secreted epithelial mucins are large macromolecules exhibiting extreme polydispersity. Mucin 2 (MUC2) is the major intestinal mucin. O-glycans attached to MUC2 form a diverse arrangement crucial for interactions with endogenous and exogenous lectins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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