Thermo Fisher Scientific MAP1LC3B Polyclonal Antibody
MAP1LC3B 단백질을 인식하는 Thermo Fisher Scientific의 sheep polyclonal 항체. Western blot과 IHC에 사용 가능하며, 자가포식 관련 연구에 적합. 동결건조 형태로 제공되며, 장기 보관 시 -20°C에서 안정적 유지 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:200–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human LC3B conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: MAP1LC3B.
Target Information
LC3B (Autophagy Marker Light Chain 3B, MAP1A/MAP1B LC3B) is encoded by the gene MAP1LC3B in humans. LC3B is associated with microtubule assembly and neurogenesis, and plays a vital role in autophagy, the process of cytoplasmic component degradation.
Three human LC3 isoforms undergo post-translational modifications during autophagy. Macroautophagy, the major inducible pathway for cytoplasmic turnover, involves double-membrane autophagosomes that fuse with lysosomes for degradation.
LC3B mediates interactions between microtubules and cytoskeletal components and may be involved in cancer, aging, metabolic, neurodegenerative, and cardiovascular/pulmonary diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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