Thermo Fisher Scientific MAP2 Polyclonal Antibody
MAP2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC에 사용 가능. 신경세포 구조 연구에 적합하며, 인간 시료에서 검증됨. 동결건조 형태로 제공되며, 4°C 또는 -20°C에서 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Immunocytochemistry (ICC/IF) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 350–400 of mouse MAP2 conjugated to a blue carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10987424 |
Product Specific Information
Reconstitute with 100 µL of distilled water.
The peptide is homologous in rat.
Target Information
MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated, and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, which is an essential step in neurogenesis.
The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins enriched in dendrites, suggesting a role in determining and stabilizing dendritic shape during neuron development. MAP2 is useful in studies of neuron structure in normal and malignant brain tissue as well as in degenerative diseases such as Alzheimer’s Disease (AD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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