Thermo Fisher Scientific CD53 Polyclonal Antibody
Western blot에 최적화된 CD53 폴리클로날 항체로 인간 및 마우스 반응성. 항원 친화 크로마토그래피로 정제된 고순도 제품. PBS/glycerol 버퍼에 보존되어 장기 저장 가능. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human CD53 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803710 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage. It forms complexes with other leukocyte surface proteins such as CD2, CD19, CD21, MHC II, VLA-4, and tetraspanins CD37, CD81, CD82, modulating various signaling processes. CD53 is involved in radioresistancy of tumor cells and exhibits anti-apoptotic effects upon triggering. In thymus, CD53 is up-regulated during T cell positive selection and is strongly expressed upon macrophage exposure to bacterial lipopolysaccharide, while neutrophil stimulation results in down-regulation of CD53 expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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