Thermo Fisher Scientific CENPA Recombinant Rabbit Monoclonal Antibody (PSH0-09)
Thermo Fisher의 CENPA 재조합 토끼 단클론 항체(PSH0-09)는 인간 시료에 반응하며 WB 및 ICC/IF에 적합합니다. 핵 및 염색체 중심체 단백질 검출에 사용되며, Protein A로 정제된 액상 항체로 안정적인 신호를 제공합니다. 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PSH0-09 |
| Immunogen | Synthetic peptide within human CENPA aa 21–70 / 140 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2942597 |
Product Specific Information
- No cross-reactivity with mouse and rat.
- Expression varies across the cell cycle, with high levels in G2 phase (at the mRNA level).
- Positive control: HeLa cell lysate, A375 cell lysate.
- Subcellular location: Nucleus, Chromosome, Centromere, Kinetochore.
Target Information
Centromeres are specialized chromosomal domains that determine the mitotic behavior of chromosomes.
CENPA encodes a centromere protein containing a histone H3-related histone fold domain essential for centromere targeting.
CENPA is thought to form a modified nucleosome-like structure where it replaces one or both histone H3 copies in the (H3-H4)₂ tetrameric core.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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