Thermo Fisher Scientific HNRNPM Monoclonal Antibody (OTI1E12), TrueMAB

Applications

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

Heterogeneous nuclear ribonucleoproteins (hnRNPs) bind nascent RNA polymerase II transcripts and are involved in transcript-specific packaging and alternative splicing of pre-mRNAs.
The M1–M4 hnRNP proteins form a cluster of four abundant pre-mRNA binding proteins that interact with poly(G) and poly(U) RNA homopolymers.
They belong to the ribonucleoprotein consensus sequence family and contain a methionine/arginine-rich hexapeptide repeat motif (MR repeat), similar to that found in the 64 kDa subunit of cleavage stimulation factor involved in 3'-end maturation of pre-mRNAs.
Homologous proteins exist across diverse eukaryotes from humans to yeast.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.