Thermo Fisher Scientific Insulin/IRDN (beta-Cell and Insulinoma Marker) Monoclonal Antibody (IRDN/805)
베타세포 및 인슐린종 마커로 사용되는 IRDN/805 단클론 항체. 다양한 종에 반응하며 IHC(P), IHC(PFA) 등에서 활용 가능. 고순도 Protein A/G 정제, PBS(pH 7.4) 보존액, 무보존제. 연구용으로만 사용.
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Thermo Fisher Scientific Insulin/IRDN (beta-Cell and Insulinoma Marker) Monoclonal Antibody (IRDN/805)
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
- Immunohistochemistry (PFA fixed) (IHC (PFA)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Pig, Rabbit |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IRDN/805 |
| Immunogen | Recombinant INS protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Does not react with Rat
Target Information
Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein, and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids.
Insulin is a 51-amino-acid polypeptide produced from the precursor peptide proinsulin, which is post-translationally cleaved into two chains (peptide A and peptide B) covalently linked via two disulfide bonds and one molecule of C-peptide.
Insulin deficiency results in diabetes mellitus, a major cause of morbidity and mortality. Insulin is also present in tumors of β-cell origin such as insulinoma.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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