Thermo Fisher Scientific CD4 Monoclonal Antibody (W3/25), Biotin
Thermo Fisher CD4 단클론 항체(W3/25), Biotin은 랫트 시료에서 CD4 단백질 검출용으로 최적화된 항체입니다. IHC, Flow Cytometry, IP 등 다양한 응용에 사용 가능하며, Biotin 결합형으로 높은 특이성과 재현성을 제공합니다. 연구용 전용 제품입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | - |
| Flow Cytometry (Flow) | 0.5 µg/1x10^6 cells | View 1 publication |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Rat |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | W3/25 |
| Immunogen | Rat thymocyte membrane |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 4–5 mg/mL BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term); at -20°C (long term). Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538778 |
Available Formats
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed in T helper cells but may also be present in monocytes, macrophages, and dendritic cells.
At the tissue level, CD4 expression is found in thymus, lymph nodes, tonsils, spleen, and certain non-lymphoid tissues such as brain and gut.
CD4 functions to initiate or enhance T-cell activation through its association with the T-cell receptor complex and Lck kinase. It may also mediate neuronal damage in infectious and immune-mediated CNS diseases.
Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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