Thermo Fisher Scientific RelB Polyclonal Antibody
RelB 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC, ICC, ELISA 등 다양한 응용 가능. Protein A로 정제된 고순도 항체이며, 안정적인 액상 형태로 -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human RelB (amino acids 401–500) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The NFκB transcription factor was originally identified as a protein complex consisting of a DNA-binding subunit and an associated protein. The DNA-binding subunit is functionally related to c-Rel p75 and RelB p68. The p50 subunit was initially believed to be a unique protein derived from the amino-terminus of a precursor designated p105. Another protein, p52 (previously referred to as p49), has been identified that can act as an alternative NFκB subunit. RelB does not bind with high affinity to NFκB sites, but heterodimers between RelB and p50 bind with an affinity comparable to that of p50 NFκB homodimers. However, RelB/p50 heterodimers, unlike NFκB heterodimers, transactivate transcription of promoters containing κB binding sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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