Thermo Fisher Scientific Phospho-Doublecortin (Ser306) Polyclonal Antibody, FITC
Phospho-Doublecortin (Ser306) 항체로 인간, 마우스, 랫트 시료에 반응합니다. FITC 결합 형식으로 형광 검출에 적합하며 Western blot, ELISA, IP에 사용 가능합니다. 액상 형태로 -20°C 어둡게 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide taken within amino acid region 200–250 on human Mesencephalic astrocyte-derived neurotrophic factor (Doublecortin, UniProt ID: O43602-1). |
| Conjugate | FITC (Fluorescein) |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX (Doublecortin) is a cytoplasmic protein that directs neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains that bind microtubules and interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase. This interaction is essential for proper microtubule function in the developing cortex. Mutations in the DCX gene are associated with X-linked lissencephaly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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