
Thermo Fisher Scientific MYBBP1A Recombinant Rabbit Monoclonal Antibody (JB40-09)
MYBBP1A 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot, IHC, ICC/IF, Flow cytometry에 사용 가능. HEK293 발현 시스템에서 생산된 IgG 형 항체이며, 높은 특이성과 재현성을 제공. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (IHC) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:10–1:50 |
| Flow Cytometry (Flow) | 1:50–1:10 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JB40-09 |
| Immunogen | Synthetic peptide within Human MYBBP1A aa 1,051–1,100 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_2848610 |
Product Specific Information
- Positive Control: A549 cells
Target Information
The Myb family of transcription factors, including A-, B-, and c-Myb genes, regulate differentiation, cellular growth, and gene expression. c-Myb is essential for hematopoietic cell proliferation and differentiation.
Myb-binding protein 1A (MYBBP1A) is a nuclear protein localized mainly in nucleoli and interacts with various transcription factors. It enhances AhR-dependent gene expression and acts as a negative regulator of PGC-1α via p38 MAPK. MYBBP1A also functions as a nucleocytoplasmic shuttling protein utilizing CRM1-dependent and independent nuclear export pathways.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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