Thermo Fisher Scientific MC1R Polyclonal Antibody
MC1R 단백질을 인식하는 토끼 폴리클로날 항체로, 인간 및 비인간 영장류 시료에 반응합니다. IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 용액에 0.1% sodium azide 포함, 1 mg/mL 농도로 제공됩니다.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 2.5–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human MC1 Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551291 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey (100%)
Baboon, Cat, Panda (94%)
Target Information
MC1R (Melanocortin Receptor 1) mediates the effects of melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH).
MSH and MC1R are key regulators of melanogenesis, controlling the ratio of red pheomelanin to black eumelanin in the skin by increasing eumelanin production.
Non-functional or truncated forms of MC1R lead to lighter pigmentation, while constitutively active forms result in darker coloration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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