Thermo Fisher Scientific CD209/DC-SIGN (Pathogen Receptor on Dendritic Cells) Monoclonal Antibody (C209/6774)
CD209/DC-SIGN 단일클론 항체로 수지상세포 병원체 수용체 연구에 적합함. 인간 반응성, Mouse IgG1, kappa 아이소타입. Flow Cytometry에 0.5–1 µg/10^6 cells로 사용 가능. Recombinant CD209 단백질 기반 면역원, Protein A/G 정제, PBS buffer 보존.
- 카탈로그번호
- 30835MSM4P1ABX
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD209/DC-SIGN (Pathogen Receptor on Dendritic Cells) Monoclonal Antibody (C209/6774)
Applications
- Flow Cytometry (Flow)
Tested Dilution: 0.5–1 µg/10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C209/6774 |
| Immunogen | Recombinant human CD209 protein fragment (exact sequence is proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
This gene encodes a transmembrane receptor commonly referred to as DC-SIGN, expressed on dendritic cells and macrophages. It functions in the innate immune system by recognizing diverse pathogens including parasites and viruses.
The protein has three domains:
- N-terminal transmembrane domain
- Tandem-repeat neck domain
- C-type lectin carbohydrate recognition domain
The extracellular region (neck + lectin domains) acts as both a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands. The neck region enables homo-oligomerization, enhancing multivalent ligand binding.
Rare variations in the number of 23 amino acid repeats in the neck domain can significantly impact ligand binding ability. This gene is closely related to L-SIGN (GeneID 10332), differing in ligand-binding properties and tissue distribution.
Alternative splicing results in multiple variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.