Thermo Scientific™

GeneBLAzer™ 5TH1A-Gα15-NFAT-bla CHO-K1 Cells

GeneBLAzer™ 5HT1A Gα15-NFAT-bla CHO-K1 cells contain the human 5-HT Receptor 1A (5HT1A) stably integrated into the GeneBLAzer™ Gα15-NFAT-bla CHO-K1 cell자세히 알아보기

GeneBLAzer™ 5HT1A Gα15-NFAT-bla CHO-K1 cells contain the human 5-HT Receptor 1A (5HT1A) stably integrated into the GeneBLAzer™ Gα15-NFAT-bla CHO-K1 cell line. GeneBLAzer™ Gα15-NFAT-bla CHO-K1 cells (Cat. no. K1537) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element and the Promiscuous G protein, Gα15.

The GeneBLAzer™ 5HT1A Gα15-NFAT-bla CHO-K1 cells are functionally validated for Z` and EC50 concentrations of 5-CT. In addition, GeneBLAzer™ 5HT1A Gα15-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

Agonists and antagonists of the 5HT receptors are in various stages of clinical trials for the treatment of neurological disorders like anxiety, insomnia, and depression.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

사양

등록 번호NM_000524

어세이 입력Cell-based beta lactamase reporter gene

셀 상태Dividing Cells

검출 방법Fluorescence

용도(애플리케이션)FRET

유전자 기호5HT1A

개체군 상태Single Cell Clone Origin

제품라인GeneBLAzer™

수량2 x 106 Cells

리포터 유전자BLA (Beta-Lactamase)

타겟 입력5HT1A, HTR1A

세포주CHO-K1

System TypeGeneBLAzer™

Druggable TargetGPCR

Unit SizeEach